The Circumpolar Flaw Lead (CFL) System Study is a major international effort under Canadian leadership that aims at understanding how changes in the physical system affect biological processes, towards a better understanding of the potential effects of climate change. The CFL project is part of the PAN-AME cluster.

CAML will investigate the distribution and abundance of Antarctic marine biodiversity, how it will be affected by climate change and how climate change will affect the ecosystem and the planet. Its key focus is a major ship based research programme in the austral summer of 2007-2008. Scientists from 30 countries and 50 institutions will collate data providing a robust benchmark against which future change can be measured.